Welcome to Signature Dermatology, located in Hilliard, Ohio located on the west side of Columbus, Ohio!

We are currently accepting new patients. Since your skin is the largest organ of the body, it deserves unparalleled attention! At Signature Dermatology, our highly-trained, board-certified Columbus Ohio Dermatologists offer the latest techniques and advances in the specialty of dermatology to diagnose and treat all conditions of the skin, hair, and nails. Both Dr. Cassandra and Dr. Costanza focus on providing comprehensive care for persons of all ages.
Your skin is our passion, and we strive to make every patient’s visit an unforgettable, Signature experience! Our practice is conveniently located just off I-270 in the Mill Run area of Hilliard, Ohio and we are very excited to serve the greater Columbus, OH area. With a beautiful, new, state-of-the art facility, we are proud to be the only headquartered dermatology practice in Hilliard.
We can offer patients very prompt appointments, and our physicians and staff make providing friendly, attentive care a priority. Come and visit our dermatology facility. It is our mission to treat your concerns with genuine care and offer you the most current medical treatments. Come meet our Board Certified Dermatologists for a full skin exam or  cosmetic consultation. 

Learn More About Our Providers

We Offer The Latest Cosmetic Treatments

Botox Columbus, OH

Kybella Columbus, OH

Patient Testimonials

  • "This practice is all about the patient. The staff is professional, they do not book multiple overlapping appointments as they understand the importance of and respect peoples time. This is all great but the real reason you need to come is the Doctors - they know what they are talking about. I was prescribed only what I needed and actually was talked out of buying all the products I THOUGHT I needed. You will not be disappointed!" -Lia H.   

  • "I have been seeing Dr. Cassandra for a year or so. Their office is exceptionally clean. The staff is professional and it's a calming atmosphere. And there is no wait time to be seen. Dr. Cassandra is very professional and caring. She makes sure you understand her diagnosis and treatment plans. I recommend Signature Dermatology to my friends and family." -Patti S. 

Shop Online For Physician Grade Products

Available skin care product lines include Obagi Nu-Derm and C-Rx, Glytone, Avene, Revision Skin Care, Elta MD moisturizing sunscreens, Blue Lizard sunscreens and our own Signature Dermatology Benzoyl Peroxide cleansers and Rx Tretinoin.